This testimony of Xenophon, from more than 2,500 years ago, is the earliest documentation of a unique phenomenon known as 'mad honey'.

But what if you are the kind of organism that can't move (like plants or fungi)? For example - let's suppose that you're an acacia tree on the African Savannah and you don't have access to very much water and therefore, the fleshy part of your leaves are very precious to you, and you would rather not have harvester ants cut them up and take them away

Smoking 5-MeO-DMT gives the person who inhales it a strong yet short lasting meeting with God. The bufo toads are probably the most prominent example of Zoopsychedelics, but are they alone?

“The urine seems to be more powerful than the mushroom and its effect May last through the 4th or 5th man.”

Amanita muscaria does not have psilocybin AT ALL. It is really something else, on the other hand, there is also the ibotenic acid, which is a turn-off.

So, in a calculated move, I decided for the first time in my life to change my consciousness proactively and simply get drunk, and that's what happened. The experiment was pleasant and successful.

The good people of NIDA made generous development budgets available to researchers who would develop synthetic versions of natural cannabinoids such as THC or CBD. The most diligent and prolific researcher who used NIDA money to this end was an American professor of organic chemistry named John William Huffman, who developed over 400 such analogs.