From personal experience, all of the materials I have developed do not produce physiological dependence,

It turns out that tobacco contains a relatively unknown MAOI called Harman

The nitrogen atom can be likened to the metal ring that serves as an opener in a can of Coca-Cola. When we want to open the can, our finger knows how to recognize the ring and pull on it, just like the enzyme responsible for activating the receptor knows how to recognize the single nitrogen atom and take the electron from it.

Smoking 5-MeO-DMT gives the person who inhales it a strong yet short lasting meeting with God. The bufo toads are probably the most prominent example of Zoopsychedelics, but are they alone?

“The urine seems to be more powerful than the mushroom and its effect May last through the 4th or 5th man.”

So, in a calculated move, I decided for the first time in my life to change my consciousness proactively and simply get drunk, and that's what happened. The experiment was pleasant and successful.

The good people of NIDA made generous development budgets available to researchers who would develop synthetic versions of natural cannabinoids such as THC or CBD. The most diligent and prolific researcher who used NIDA money to this end was an American professor of organic chemistry named John William Huffman, who developed over 400 such analogs.